I just completed my 5 years of AI. YEAH!! It's a long journey - but you can do it. I was on anastrozole for the first 11 months - then was switched to exemestane. My hand join pain on the first drug was intolerable. Mostly my side effects were insomnia & hot flashes, my hair thinned a bit - but not really noticeable. I take CALM for sleep in gummies - it's basically magnesium. Also any AI just sucks the moisture out of your body - so dry hair/skin, etc. My worst side effect from that was chronic constipation. Well - 9 days after stopping the AI, no more constipation - it's wonderful. They asked me to take it for another 5 years - so 10 years total, and I refused. It was only going to reduce my chances of reoccurrence by < 3%. 5 more years is just not worth it to me. I'm 68 now. I had stage 1 with lumpectomy, no lymph node involvement, 21 radiation treatments, no chemo. I'm hoping the insomnia will resolve itself eventually.