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Lupron: Anyone have muscle weakness and severe leg pain?
Prostate Cancer | Last Active: Dec 18, 2025 | Replies (69)Comment receiving replies
Lupron severely adversely effects your muscles. I have difficulty getting out of my chair and unstable in my walking. Gleason 9, CR, aggressive, locally advanced. I am told that it helps to keep me alive so I willingly accept the side effects. I was taken off all meds 10 months ago but I still feel side effects from Lupron and Erleada
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I can surely understand. My daily 3 mile walk, which is fairly elevated is
much more difficult now than before hormone treatment. Hips down to
the feet. Ibuprofen helps slightly. Little feedback from the urologist, and
oncologist!