I can only tell you what I am doing. I had endometrial cancer very small but had total hysterectomy. Doc said 4% chance of getting. Everything out. Doc checks me every three months and now next check in April. Then 3months ago got breast cancer. 11mm. Took two months to have get surgery. It was 13mm out. Not in lymph nodes. Not in margins. Doc did not do radiation and my oncotype DX was 16. So no chemo. If I took antiestrogen drug the chance of cancer recurrence is 4%. If I don't 't take the chance is 8%. 4% difference is not much more risk. If I take the arimidex side effects are body aches, blood clots and osteoporosis. I already have RA that methetrexate is keeping me sane and has taken pain away and swelling of hands gone. I am thin and would get osteoporosis. I am on the border now with osteopinia. 8% probability of getting my can back is low. And taking the antihormone drug has to many. Side effects for me. I am seeing my oncologist in a month and we will discuss again but right now I am leaning away from antihormone. You have to weigh all the pros and cons and decide for yourself with your docs. Good luck!