Between 7.5 and 5 I had major fatigue also. I am at 4.25 now and find the fatigue is lessening slightly. Perhaps challenging the adrenal gland to pick up the slack in cortisol production is a factor. I have been dropping the dose by 0.25 mg. every week or two but am ready to increase if fatigue and fuzzy thinking increase too much. With each drop there are a few days where I want to backtrack. I pay attention for symptoms of adrenal insufficiency and gca. I do miss the energy boost and lack of joint pain I had at higher doses of Prednisone. I think pmr did some damage to my joints and muscle strength during the two months before diagnosis and treatment.