hello sorry about my delay in responding, my sister is 58,has stage 4 metatastic, her first treatment was awful, her chemo is gemcitabine 1600mg, abraxane ivpbv200mg 40 ml,and she is doing a trial drug called elarglusib (9-ing-41). I don't know if all of these drugs that she took during her 1st treatment helped or not,but they completely knocked her out for several days and when she did get up she wanted to lay right back down. it's really hard seeing her like this, and she is suppose to go through this through June of next year every single week,and only feeling better and still not 100 percent 2 out of the 7 days a week, before she repeats the vicious circle again, it's gonna be hard for me to push her to go through all this, when I'm not sure it's worth it myself it seems to me that she is trading alot of good days for extra time on earth to suffer more...p.s. she is also losing to much weight and has such a restricted diet because she is also diabetic now. thank you for chatting with me it helps to talk to someone who has or who is going through the same thing she is. glad this group is here and so hopeful, god bless you all