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Morning misery: Is prednisone effective 24 hrs? PMR and hands

Polymyalgia Rheumatica (PMR) | Last Active: Dec 15, 2023 | Replies (58)
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@salmountain

PMR just does not seem to have any clear pattern in the way it causes pain.
I have gone from 20 mg to 12 mg. I take my prednisone at 6:30:a.m. I wake up in pain and have to wait about 2 hours until I am pain free. Sometimes my calfs hurt sometimes it os my shoulders, tops of my arms ,wrists and hands.
I’m hesitant to drop the dosage of my Prednisone. Just trying to deal with this without suffering the long term side effects of the prednisone.
My Rheumatologist explained that PMR pain is symmetrical and it certainly with me is.

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Replies to "PMR just does not seem to have any clear pattern in the way it causes pain...."
megz | @megz | Nov 2, 2023

Have you considered splitting the dose? I take the main dose in the morning, 5.5mg, and a smaller dose of 2mg at 6.30pm with my evening meal. My total dose is 7.5mg and I am reducing from the morning dose, leaving the later dose the same. There is no morning pain.

Most doctors say to take the whole lot in the morning, but that defeats the purpose of treating morning pain which is the biggest problem.

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