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Pancreatic cancer relapse

Pancreatic Cancer | Last Active: Nov 1, 2023 | Replies (69)

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@mjennison

Hi,
I am reading alot of posts lately and wanted to write in and see if anyone had the experience my husband is going through. Sept. 2022 diagnosed with Pancreatic Cancer (head of pancreas) and went through 8 cycles folfirinox neoadjuvant chemo. Whipple Surgery performed on Feb. 15 2023. Recovery went well and margins were clear, no lymph nodes infected. Staged at IIB. May 2023 started on 4 cycles of post whipple folfirinox chemo. CA-19 has been great up until Sept when it rose to 60 and then 212 4 weeks later. CT Scans are clear and no signs of metastatic disease. We saw our oncologist today and he is scheduling another CT Scan in 4 weeks and was not very encouraging on next steps (almost like wait and see what comes on the scans in order to determine how to treat). We have contacted Mayo clinic for a 2nd opinion and they have all scans/notes/etc. and we expect to hear from them this week. Has anyone experienced a rise in CA19 and clear scans? what did you do next? Thank you so much!

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Replies to "Hi, I am reading alot of posts lately and wanted to write in and see if..."

I'm not in that situation, as I haven't had the Whipple (don't qualify due to tumor location). My oncologists told me that some metastases are actually very flat lesions. Because they're not three-dimensional, they don't show up on CT scans. On my last scan in September, my liver and spleen were described as "unremarkable," yet we know that in April, during the staging laparoscopy, the surgeon saw at least one flat lesion outside my pancreas. I'm not a medical professional, but that might explain why the scans are clear but the CA 19-9 indicates activity. You could add that to your list of questions for your MDs.