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I’m Not Responding to Prednisone and I Need Advice

Polymyalgia Rheumatica (PMR) | Last Active: Nov 24, 2023 | Replies (72)
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@johnbesaw

My doctor just told me after a month waiting for results that I had PDR prescribed 5 mgs of prednisone per day.
I have been taking it for a week now and no signs of improvement yet. I have to wait another month for my next appointment. I feel like doubling it after reading all the comments above. Can it take 2 weeks to get results?

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Replies to "My doctor just told me after a month waiting for results that I had PDR prescribed..."
John, Volunteer Mentor | @johnbishop | Oct 30, 2023

Welcome @johnbesaw, I think most starting doses for PMR are within the 15 mg to 25 mg of prednisone range. I can't imagine that 5 mg would relieve the pain. Here's more information on the topic:

"The mainstay of treatment of PMR is oral prednisone therapy. According to the latest EULAR/ACR guidelines, prednisone therapy should be within the range of 12.5 to 25 mg, using the minimum effective dosage to achieve remission. Tapering should be individualized once remission is achieved."
--- Polymyalgia rheumatica: An updated review: https://www.ccjm.org/content/87/9/549

Are you able to call your doctor or get a referral to a rheumatologist for a second opinion?

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art43 | @art43 | Nov 1, 2023

I had severe pain. Initial dose of 20 did nothing. After 4 days, doc increased dose to 30. Pain gone in 24 hours. Started taper of 5 mg every 2 weeks. Now down to 20. Still no pain ever.

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