OK - I am not a medical professional, but what I have read from survivors is that many continue with chemotherapy - tailored, but they continue. Many for years. Terminating chemo, imo uneducated opinion, is not what I would do under like circumstances.
Some folks cannot tolerate more chemo, but in many cases they try to continue with the same chemo, vs tailoring.
I will again note, that unless you are being treated at a center of excellence for pancreatic cancer, you are not getting front line treatment - this isn't to say the medical professionals in your area aren't working hard and trying to do the best for you possible, it is simply because they do not specialize in pancreatic cancer - pancan is not like other cancers. It's survival rate is low - your best chance will always be at a place like Mayo (Rochester, not Jax or Arizona), MD Anderson, Memorial Sloan Kettering, etc.
Excellent input