If you can manage without them by doing air way clearance, of course that’s easier on your system .
I stopped my big 3 after 3 months because I had hearing loss. But I got sick again; that is, fatigue and shortness of breath, which incapacitate me. So I’m back on a different 3 antibiotics again .

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As others have said, get on an airway clearance routine, usually nebulizing 7% saline and using an Aerobika (twice a day) to clear the mucus out of your lungs. I also use the free Autogenic Drainage App (free) which helps me get the gunk out. The saline is important because it helps thin the mucus but also helps makes the lungs inhospitable to the NTM. It is possible to keep the NTM tapped down by these procedures and keep from getting worse or having to take the antibiotics. I was diagnosed 2 years ago and have been doing this without getting worse and without going on the antibiotics. Many others too. Depends on how sick you are and your symptoms whether you need to take the antibiotics or not.