Three years ago, I wasn't on any prescription drugs and felt great. The only thing I would take is the occasional ibuprofen. Since then, I've been on up to three Rx's at a time--each prescribed by a different doctor. There are definitely known negative interactions. All three of the doctors, at some point expressed serious concerns about the other Rx's. I couldn't get any good and consistent medical advice, so I made a decision to stop two of the drugs. Like you, I can't say for certain what caused my hair loss. It may have been the combination. What I do know, is that, once Prolia was in the mix, the hair loss was not to be ignored.