Did your doctor explain why he wants you to start them all at once? I had a cranky old pulmonologist, and didn't know any better, so I started them all at once. It was tough!

Later, I also went to an ID doc in the same clinic, and as he read my record, he commented that their protocol was to start them one at a time "But Dr A does things his way." When the ID doc changed my meds from 3X/week to daily because I wasn't getting better, we did it one at a time, with a week lag between. That was almost 5 years ago, now he would probably add Arikayce instead.

I did get vaccines while I was on the meds, and I don't remember it being any problem - they work on different parts of the immune system. But as you are saying you have no symptoms, and MAC grows slowly, would the doc be okay with waiting a month?

Of course, keep up the airway clearance. And maybe get a start on a good probiotic and start eating extra high protein foods to build up your body while you wait.

All that said, I guess it all comes down to how much you trust the doc - is he a pulmonologist, and does he seem up to date on matters like airway clearance and 7% saline?
Sue

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