I'm on cyclosporine, mycophenalic, and prednisone for my transplant and I'm 22 months post transplant at age 43. Never had joint issues prior to xplant, but now my knees have been giving me horrible pain for 1 year and now the bottoms of my feet for the past 5-6 months. It feels like the bones are almost being pressed on in both areas as there is just pressure there I've never felt before. all my knee xray imaging has looked quite good/normal and same with feet, and podiatrist said it didn't seem to be neuropathy bc I have good feeling in my toes, But I know I have had strong temperature sensitivity past 1.5 yrs in extremities. Can someone advise me as to what might be happening and if possibly likely immunosuppressant related. 43 years old and I'm pretty skinny. Thanks all.