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Began folfirinox treatment - have a few questions

Pancreatic Cancer | Last Active: Oct 27, 2023 | Replies (54)

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@jk77

Regarding nausea: I had good results with generic Zofran and generic Phenergan. The latter made me tired, so it was also helpful for overnight. And, the instrux were to stagger the drugs -- that if Zofran didn't last the full 8 hours (it didn't), I was allowed to take Phenergan at hour 6 or so.

My onc. initially wrote for generic Zofran and generic Compazine; the latter is well-known as an anti-nausea drug.

I'm too tired to look up the generic names, but drugs(dot)com is a very helpful website for such stuff, including side effects. Good luck.

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Replies to "Regarding nausea: I had good results with generic Zofran and generic Phenergan. The latter made me..."

Thanks for your reply.
Unfortunately, he's unable to continue with the Zofran due to the side effects (he was having breathing difficulties in addition to some of the other side effects). The nurse practitioner prescribed Ativan. He didn't start that yet since he's concerned about the side effects. Both the oncologist and the nurse practitioner are aware that he's extremely sensitive to most medications. Right now, he's of the mindset of dealing with the nausea which he's used to vs the risk of taking a new medication and what unknown side effects he might have. We're hoping that the vestibular issues he's still having from the vertigo attack resolve soon because on top of the nausea, he's still having motion sickness when turning over and when getting out of bed.