Anyone else starting drugs after long break?

Posted by vansks @vansks, Oct 12, 2023

About 30 years ago I fractured my pelvis in a fall and was diagnosed with osteopenia. I took Fosamax followed by 2 years of Forteo, then 2 years of Reclast. After all that I still had osteopenia. I became terrified of possible side effects, particularly jaw wasting disease, and discontinued treatments. Over the years I slowly progressed to osteoporosis. I foolishly thought I'd be fine as long as I stayed above -3, but my latest Dexi showed a jump to -3.1. Now I'm being referred to a bone fragility clinic and I'm again terrified. I'm 73. Any advice on what might be most useful for me?

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You might consider Forteo again. The second application is said to be as robust as the first. You know how it affects you. And you don't have to worry about osteonecrosis with Forteo. Tymlos would be another good choice. I prefer Forteo because it is a lesser dose without preservatives. The black box warning limiting you to two years has been removed.
You may be offered Evenity or Prolia, best not. But Forteo is better.
I've been taking since April at 72. I so like this drug.
Best luck!

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@gently

You might consider Forteo again. The second application is said to be as robust as the first. You know how it affects you. And you don't have to worry about osteonecrosis with Forteo. Tymlos would be another good choice. I prefer Forteo because it is a lesser dose without preservatives. The black box warning limiting you to two years has been removed.
You may be offered Evenity or Prolia, best not. But Forteo is better.
I've been taking since April at 72. I so like this drug.
Best luck!

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Thank you! I was leaning towards Tymlos because I heard there were less side effects, but I think I tolerated Forteo well the first time, and I like no preservatives. I think my mediocre bone building results may have been due to my frequent ibuprophen use. My daughter sent me an article stating ibuprophen could even increase bone loss if taken with Fosamax. I took it for muscle and tendon issues I attributed to my job. (I'm retired now and never take it anymore.)

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@vansks

Thank you! I was leaning towards Tymlos because I heard there were less side effects, but I think I tolerated Forteo well the first time, and I like no preservatives. I think my mediocre bone building results may have been due to my frequent ibuprophen use. My daughter sent me an article stating ibuprophen could even increase bone loss if taken with Fosamax. I took it for muscle and tendon issues I attributed to my job. (I'm retired now and never take it anymore.)

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vansks, good daughters are wonderful.
The bone building effects of Forteo and Tymlos are blunted by prior use of bisphosphonates. And there are rumors about dosing intervals other than every day that may build more bone. It may be true that tymlos has fewer side effects, but I have doubts since the dose is higher. I have a lingering idea that even the Forteo dose may be higher than what might be the most advantageous for incremental bone. Either is a great choice. Retirement is amazing. I didn't realized how many of those little aches would disappear.

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So happy to find this site after 10 years of no confidence from fosamax experience ,am in dire need of bone care as just had bone test density for my bones ,they informed me they are in need of help ,really not looking forward to the experience of fosamax ,leaning toward forteo but very skeptial

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Hi Meredith, was your former Fosamax experience poor results, or bad side effects? I am also not doing Fosamax again. One of my concerns is the long wait to find out if treatment is helping. My insurance only allows a Dexa scan every 2 years. Whatever you choose, I hope it helps!

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@vansks &@meredithraynor-there is the option of you having another DEXA out of pocket, I’m told they are not that expensive ~125.00 is what I’ve heard. If bone markertests were done before you started treatment , you could repeat them to check out if it’s helping or not along the way— but I assume that was not done. Wishing you luck!!

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I stumbled upon this post and decided to do a little reading up on Fosamax aka Alendronate. I’m currently suppose to be taking this medicine for OA. Unfortunately I have difficulty remembering to take my meds daily on a regular basis. After reading the side effects that may not be a bad thing. I read that it can cause the thigh bone to break. I had a THR on the right in 2020 and am fixing to have the left
Done. Also I
Noted the doctors teaching assisted seemed to believe I should be on a vitamin D supplement also if taking this medicine, which I am not. No one ever said too.

Any advice would be greatly appreciated. Thank you and best wishes for you all.

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Hi Darlas1967, I haven't heard of Fosamax for OA, isn't that osteoarthritis? Possibly you also have osteopenia or osteoporosis, have you had a Dexa scan?
Taking Vitamin D is a must for me. Dr recommends 2000 units in summer and 5000 in winter daily.
There is an option to take a once weekly dose of Fosamax, but I suspect the milder daily dose would have less risk of side effects. Just a layman opinion! I think if you keep working on remembering your daily dose it will become a habit for you. Good luck!

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I had a consult with a bone fragility clinic yesterday. I've opted to try Tymlos. Dr didn't feel it was necessary to do a bone marker test. I've found a local lab that will do a NTx test for under $100 out of pocket. I'm going to get it before starting Tymlos for my own information. I can do an out of pocket Dexa scan for $169. In a year I'll do that to see how the Tymlos is working.
My Dr said she's had patients get good results from taking collagen peptides . She also recommended eating 2 prunes a day. She said it's a super food for bones.

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5- 6 prunes a day is what I’ve been told and read

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