I am a completely unique case. I was planning not to take them because the studies I read said that androgen deprivation did not make any difference in overall biochemical reoccurrence or survival in men over the age of 70 and I was almost 74 when I had the radiation. That said, I have been on testosterone replacement since 2008 and when I stop applying my Androgel I go castrate in less than 60 hours. My radiation oncologist wanted to jab me so bad he could taste it and tried to jab me on my first visit. He said my observations were not good enough and tested me twice and both times my testosterone levels were under 12 ng/dl which is lower than a Lupron shot says it will get you to. I am seeing a urologist at Mayo who will give me my testosterone and monitor my PSA levels closely. I recently started back on my Androgel exactly 8 months to the day since I stopped, and my latest T level was still less than 12 ng/dl even though all my pituitary hormones were normal. It is sending the signals, but the boys are not answering even after 8 months. Why did I stop after the studies say it made no difference? Just hedging my bets because I don't trust almost anything that the medical profession or our government tells me. Remember the covid lie? If you get the jab, you won't get covid, spread covid, get hospitalized from covid or die from covid and you won't kill grandma? I do. My oncologist also wanted to give me 28 radiation treatments until I told him I was looking at doing CyberKnife with its 5 treatments and all of a sudden, he said "Oh we can do 5 too". Guess who is a co-author of a six-month Lupron jab and 28 proton radiation treatments and your first guess does not count. Be your own advocate and there is a ton of studies on the internet. My PSA had been between 2.9 and 2.3 for over five years.