@lashu you might want to look into the reasons for the black box warning. When compared with placebo, one study I read said that there was no increase in cardiovascular events with Evenity, but when compared with alendronate, Evenity has more. One reason might be that alendronate has a preventive effect so comparions with Evenity might make Evenity's risks look higher. Again, I read this and don't know the date or the most recent research on this. Maybe your doc can explain.