It's my understand that AI cuts in half the chance of recurrence. My type of cancer -- lobular -- had what my doctor calls "a long tail," meaning, if you plot recurrences out on a graph, the chance never really disappears. But it's SUCH an individual decision! I stayed on AI for 12 years -- by choice -- for the sake of my daughter. (I lost my own mother to multiple myeloma, one of those deaths that give cancer its bad name.) But after 3 fractures, I decided Enough was Enough. But again, it boils down to which scenario repulses you the most. That's why there can't really be a "standard of care." There can just be recommendations that patients accept or reject.