I took 36,000 3x per day for the first 8 mos. Then took papaya pills when creon became unaffordable ($2500 per bottle). I didn’t experience diarrhea but did experience pain if I didn’t take it before eating. After taking papaya pills I found out I didn’t need to take those either and now I take nothing. However due to my now diabetes type 1 situation I’m careful with what I eat which is mainly low carb and low sugar. Maybe low carb and sugar diet would help?