My husband has irreversible chemo induced neuropathy which started as a side effect of oxiliplatin. He takes Xeloda 3000mg a day. Gabapentin plus cymbalta plus over the counter Nerve Renew (b vitamins) has controlled it fairly well. Stage IV rectal cancer with liver metastasis. 20% urea cream helped with skin cracking and peeling. But the disease is stable after 16 mos so that’s good.