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Pancreatic cancer spreading to liver

Pancreatic Cancer | Last Active: Oct 23, 2023 | Replies (13)

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@markymarkfl

@michaelhunn7474 ,

Surgery might still be an option, but it depends on how much spread there is. You could ask about HIPEC surgery in general. You could also ask about a specific HIPEC trial going on at Mayo in Rochester with Dr. Mark Truty, Dr. Cornelius Thiels, and others. It might be this one, with Dr. Travis Grotz listed as the principal investigator: https://clinicaltrials.gov/study/NCT04858009

I also have peritoneal mets, but was not accepted for this study.

There's another one starting up at MD Anderson that was primarily designed for ovarian cancer but is accepting pancreatic cancer patients. Both often get peritoneal mets. This one takes a tissue sample from one of your tumors, and trains some of your "NK" (natural killer) cells to attack it, and then injects those back into your peritoneum via a port. https://clinicaltrials.gov/study/NCT05922930

There is also a trial pair underway called BASECAMP and EVEREST. These are based on training CAR T-cells to attack your specific tumor(s). You might qualify if your blood and tumors have certain properties. Mayo, Anderson, and many other big centers are participating in these:
BASECAMP-1: https://clinicaltrials.gov/study/NCT04981119
EVEREST-1: https://clinicaltrials.gov/study/NCT05736731
EVEREST-2: https://clinicaltrials.gov/study/NCT06051695

There are others that depend on specific mutations you may have. Pancan.org and cancercommons.org are both very helpful resources when researching clinical trials.

Wishing you the best!

--mm

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Replies to "@michaelhunn7474 , Surgery might still be an option, but it depends on how much spread there..."

Most definitely look into HIPEC and Dr. Grotz at Mayo in Rochester. I've had the procedure twice to kill the cancer in my paratenium. I can't say that it was 100% effective ... then again I can't say that it wasn't. the battle has now moved to my liver. The thing is ... you have to keep fighting! Cancer is an ugly and nasty beast ... but it is beatable! THERE ARE SURVIVORS! Keep fighting .. never give up!