I hadn't thought about the baking soda rinse. Glad that helps! Re anti-nausea med before chemo, two things. First, what premeds does he get at chemo? Mine include Zofran, dexamethasone and Emend; all are designed to combat nausea, and they're administered via the port before I get any chemo drugs. Second, I have prescriptions for both oral Zofran and oral Compazine. I was told to alternate them as needed to control nausea at any time during the chemo cycle. If the Zofran alone doesn't work, maybe the combo would.