I see a lot of literature emerging about less intrusive treatment plans for women 70-over w/ precursor or early invasive cancers. I've also seen that 5 mg Tamoxifen is considered an effective dose now for DCIS.

I'm 57 and have so many comorbidities that, though newly dx w/ Stage 1bN1 w/ mast, I'm declining radiation & any HT, at least for the time being. i'm already debilitated as it is. I've cut out all alcohol & also lost 20 lbs & am transitioning to well-doc low-carb diet to stop helping tumor cells w/ loads of glucose/fructose. I need exercise & much more community, and HT will preclude my rebuilding any of that, which is also documented as a great risk factor.

Everyone has to choose for him/herself. There are great conversations on breastcancer.org debating the risks and benefits of HT and lots of support if you decide to pause/postpone or even desist.

My hope is I could rebuild my life enough to take very low dose. In the 2018 Italian study that demonstrated the wisdom of 5 mg Tamoxifen vs 20 mg, there were even data supporting 1 MG! Apparently, the "20 mg" was only chosen--they said this at the conference--because it was the highest dose that "wasn't toxic." As usual, they didn't believe women's side effects or really care--it was just, what can protect the companies from lawsuits. Attendees & panelists commented (this presentation is on Youtube, actually) that there's no money in conducting studies on reducing dosages, because the drug companies that fund ones that are comprehensive enough to challenge "standard of care" don't see any money in discovering the effective dose at which women will more comfortable. Sad, isn't it?