Adding Oral Estrogen on Post menopause woman

Posted by sandy0257 @sandy0257, Jul 12, 2023

I’m 66 years old with no breast cancer. Do any of you have experience adding a low dosage oral estrogen to maintain or encourage bone growth?

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@teb

thank you for the detailed description of how Forteo actually works. If you find any information on altering the pattern of injection for greater efficacy, I'd love more info on that. At some point, I will likely go back on Forteo so this information will be very helpful (and hopefully to others too). Wouldn't it be great if ultimately less is more!

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@teb

I went on HRT at about 62 years old. I was lucky in that I had a doctor whom I was able to convince that it was the best option for me. As someone with autoimmune issues, I did not want to go on anything that would further mess with my immune system and he ultimately agreed. If you don't want to go on Reclast afterwards and want a script for HRT, Alloy Health may be the way to go. An MD will review your case at no cost, determine whether you are a good candidate and if so, write the prescription. If you want a personal consult with one of their docs, the cost is $35. Cost for the medication is virtually the same as through any doctor prescribing it as at our age, insurance won't cover it (but it's not expensive out of pocket). It's really a great service, helping women who want HRT as most doctors are still reluctant to prescribe especially once you are well into menopause. The other alternative is finding a doctor certified as a menopause specialist and you can find a database on the North American Menopause Society website (if you are in the states). I am seeing a menopause specialist, Dr Felice Gersh, here in SoCal and she is extremely experienced and knowledgeable. When I initially went on hormones the philosophy was "lowest dose, shortest amount of time" but that mindset is shifting due to the revelations on the faulty analysis, confounders and misrepresention of the WHI study. I'll be seeing Dr Gersh again in a couple of weeks and based on our last discussion, I think it is likely she will be increasing my dose for greater effectiveness at maintaining my density (along with many other things). The only downside to going the route of personal appointments with a menopause specialist is the very high cost of a visit as many of them do not accept insurance. So, the alternative is the online service but for me, a lengthy analysis and discussion was really important so I opted for the specialist. Once I'm established with her and we figure out best dose, I may just switch to Alloy and continue on.

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Hi @teb. I live in Canada, so I’ll have to figure out how to find an experienced specialist who advocates estriol for post menopausal women here.

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This is the 2015 study that indicates weekly is equal to daily teriparatide https://pubmed.ncbi.nlm.nih.gov/25961136/
The Tower studies in Japan

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ans, a well known bone expert at Stanford told me that it makes no sense to take Forteo for longer than three months because the bone markers will tell you that after three months the coupling action of osteoblast and osteoclasts causes a rise in osteoclasts that overwhealm the benefit of additional osteoblasts. I would be interested in McCormick's take.
The bone expert prescribes three months of Forteo followed by three months of a bisphosphonate and then back to three months of Forteo. He follows the bone markers for each patient.
The endocrinologist I've been seeing long term tells me that the Felicia Crosman studies have been disproven. But I can't find documentation.

Thanks, already, for asking McCormick.

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@gently

ans, a well known bone expert at Stanford told me that it makes no sense to take Forteo for longer than three months because the bone markers will tell you that after three months the coupling action of osteoblast and osteoclasts causes a rise in osteoclasts that overwhealm the benefit of additional osteoblasts. I would be interested in McCormick's take.
The bone expert prescribes three months of Forteo followed by three months of a bisphosphonate and then back to three months of Forteo. He follows the bone markers for each patient.
The endocrinologist I've been seeing long term tells me that the Felicia Crosman studies have been disproven. But I can't find documentation.

Thanks, already, for asking McCormick.

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Thank you for the link to that study. That's very interesting. My experience on Forteo was that I gained density the first year and lost very slightly the second which backs up that finding. That loss could have potentially started much sooner but the dexas are only done on an annual basis. I'd also love to know McCormick's understanding of this. Would you mind sharing the name of the bone expert you consulted at Stanford?

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@lynn59

Hi @teb. I live in Canada, so I’ll have to figure out how to find an experienced specialist who advocates estriol for post menopausal women here.

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Bummer. I wonder if there is something similar in Canada. Anyway, if you find someone who will prescribe HRT for you, it will likely (hopefully) be estradiol rather than estriol.

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@teb

Thank you for the link to that study. That's very interesting. My experience on Forteo was that I gained density the first year and lost very slightly the second which backs up that finding. That loss could have potentially started much sooner but the dexas are only done on an annual basis. I'd also love to know McCormick's understanding of this. Would you mind sharing the name of the bone expert you consulted at Stanford?

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David Karpf

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