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Alpha lipoic acid for Neuropathy

Neuropathy | Last Active: Oct 25, 2023 | Replies (116)
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@bettyg81pain

I'm confused - one bottle of 200 mg "Pure" Alpha Lipoic Acid capsules recommends taking 1 capsule a day-another bottle I have NAR-Alpha Lipoic Acid 600 mg instructions say take 2 daily. What does "Contains no S-Alpha Lipoic Acid" mean? Anyone familiar with either of these???

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Replies to "I'm confused - one bottle of 200 mg "Pure" Alpha Lipoic Acid capsules recommends taking 1..."
John, Volunteer Mentor | @johnbishop | Oct 15, 2023

Hi @bettyg81pain, You will notice that we merged your post into an existing discussion on the same topic here:
--- Alpha lipoic acid for Neuropathy: https://connect.mayoclinic.org/discussion/alpha-lipoic-acid-2/.

R-Alpha Lipoic Acid is the form found naturally in the body and S-Alpha Lipoic Acid is a synthetic byproduct created during the production of Alpha Lipoic Acid. Here's a little more details with a better explanation of why you want R-ALA vs S-ALA.
"Following the ingestion of R,S-lipoic acid, peak plasma concentrations of R-lipoic acid were found to be 40%-50% higher than S-lipoic acid, suggesting better absorption of R-lipoic acid." --- Lipoic Acid: https://lpi.oregonstate.edu/mic/dietary-factors/lipoic-acid

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