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Adding Oral Estrogen on Post menopause woman
Osteoporosis & Bone Health | Last Active: Oct 15, 2023 | Replies (59)Comment receiving replies
Intermittant PTH stimulates bone growth. Constant PTH causes bone loss. Paradoxically!
An injection of Forteo which is a portion of the parathyroid hormone floods the blood stream. Through a series of chemical responses, pth stimulates your kidneys to return departing calcium from the bloodstream back into the bloodstream; takes calcium back from the bone; activates 125D.
I speculate that taking calcium from the bone jump starts the effect that the osteoclasts exert on bone remodeling, stimulating the osteoblasts to lay down all the calcium gathered from those various sources. An effect enhanced by the availability of 125D
I'm fascinated by the process and have been trying to find a precise description of the timing of the chemical cascasde caused by daily injections of Forteo. There are rumors of more effective intermittancy patterns (that is longer periods between injections--daily or weekly).
I've been on Forteo since April. The P1NP bone markers for new bone have gone from 65 to
117. I so like this drug.
Good thinking, teb.
Replies to "Intermittant PTH stimulates bone growth. Constant PTH causes bone loss. Paradoxically! An injection of Forteo which..."
@ gently and @teb - I too would VERY MUCH like to hear follow up information on this idea of intermittent injections. Thank you for that information as I’ll be delving into this. I have a follow up with Dr. McCormick this week and will ask that very question!!!
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thank you for the detailed description of how Forteo actually works. If you find any information on altering the pattern of injection for greater efficacy, I'd love more info on that. At some point, I will likely go back on Forteo so this information will be very helpful (and hopefully to others too). Wouldn't it be great if ultimately less is more!