Thanks for your detailed reply. You've done wayyyy more research than I. I'm just too worn out to dig deeply. The whole thing gets demoralizing although, generally, I'm an upbeat person. I go to a one hour exercise class 5 days a week. That has been the most substantial thing that addresses my cramps. Gabapentin also helps with sleep, 800 before bed. Keep me posted on ahay else you've tried and how you're doing.