I also have questions about Trodelvy. My wife is HR+/HER-, and has been on Verzenio and Faslodex for three years. Her MRI and PET scans in July showed the bone mets were lit up, and that the cancer had spread to the liver. She didn't want to do chemo yet, so her oncologist put her on Letrozole, and it unfortunately did not work, the newest scans showed the liver mets had grown. Her onc has recommended Trodelvy, she only has a week to decide if she wants to pursue it or not, and she is well aware of her other option. Anyone out there on, or been on Trodelvy ? Would love to hear about others experience on it.