For two years, I have said "no" to using Duloxetine (Cymbalta) for my post-stroke nerve pain. I do take a rather low dose of gabapentin, but I just am so afraid of drug side effects. I've consulted with three different neurologists and two physiatrists, and they ALL have recommended Duloxetine as the preferred treatment to reduce (not eliminate) the burning. Finally, after suffering so much all this time, I decided to commit to it and see if it helps, and have added to the gabapentin. After two months, I think it's working! I have chunks of time in most days where I am aware that the pain is less intense and I feel better. I slowly went up to the recommended 60 mg dose recommended, and the only side effect is some constipation, which can be managed.