I totally agree....I tried 30mg of Cymbalta and while it made me feel amazing after taking it for 5 days I had no bowel movement and was miserable. I already take Amatiza for constipation issues and I can't deal with feeling miserable from the constipation it gave me. I even tried going to the 20mg daily and it did the same thing so I had to stop taking it as much as it helped the pain and arthritis I have. I can't take nsaids and so other than cortisone there's not much I think I can take since I can't take things like Cymbalta and Nsaids and Tylenol doesn't really cut it and I don't want to take any pain meds because they also constipate if taken too much. I wish you luck and keep us updated how the every other day works for you. I never tried taking it this way.