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Began folfirinox treatment - have a few questions

Pancreatic Cancer | Last Active: Oct 27, 2023 | Replies (54)

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@colleenyoung

Hi @lisn, I moved your questions about side effects of FOLFIRINOX treatment for pancreatic cancer that has metastasized to your earlier discussion where you can connect again with members like @ncteacher @markymarkfl @mimimmx @kjc12 @ch1co2 @jk77.

I'm hoping that they will have tips for dealling with sickly sweet taste that your husband is experiencing. How has the fever been managed? How is he doing? And YOU?

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Replies to "Hi @lisn, I moved your questions about side effects of FOLFIRINOX treatment for pancreatic cancer that..."

Thanks for tagging me, Colleen! I haven't had any issues with a sickly sweet taste after chemo. If anything, my taste buds have been somewhat blunted, making food seem less flavorful than before. Even this, though, has subsided as my treatment has progressed. Perhaps there's a way to doctor the food to give it a better flavor that overrides the lingering sweet taste. For example, years ago, when I received carboplatin for ovarian cancer, I had a metallic taste in my mouth. I switched to kosher salt for meals--regular salt "disappeared" on food--and mint Tic Tacs worked well between meals. You'd need to experiment a little to find the best solution for your husband.

Re fever, I haven't had that either. The only time I presented at chemo with a fever was when I had what ultimately was a gallbladder attack, back in July. I do see that fever can be one of the many side effects of oxaliplatin, so the nurse may be correct. I was originally prescribed an oral dose of dexamethasone, which I also get via IV as a premed, but I haven't taken it since cycle 2, I think. It seemed to cause hiccups, and I really haven't needed the extra support since then anyway.

@lisn , I hope you all have been able to solve these problems. Please let us know!

Thank you Colleen. He just finished his second treatment and he had a fever again. The team said that it's the Oxaliplatin. The remedy was going to be steroids on days 2 and 3, but he feels worse from the steroids so he's not taking them, managing the fever with Advil. However, the nausea is present all the time. Thanks to everyone's suggestions, he's been getting hydration on treatment day and now on disconnect day as well. I gave him a mint to put in his mouth when treatment started but he still got the taste and still has it 3 days later. I am doing well thank you. This forum has been so helpful and informative!