My husband is the one with the issues. They did a kidney biopsy to determine the ANCA Vasculitis. They just lowered the prednisone from 60 mg to 40 mg. He has no energy, can’t sleep and what scares me is that his thought process is not there, has a really hard time concentrating. Did you have that issue? Hope and pray it gets better as he starts tapping more off of prednisone. He also has gotten shots of rituximab and is now getting a shot every week of epoetin