While we're on the topic of safety with nasal saline products, I want to report a recent experience I had with other-than-NeilMed saline packets. I purchased some equate brand saline packets in Walmart. While the rinsing felt the same as NeilMed packets, the salt in the equate packets was clumpy and difficult to empty into the squeeze bottle, almost as if they'd gotten wet or damp. Equate brand was made in India, not sure where NeilMed ones are made but from now I'm sticking with NM for saline packets as quality seems much better than equate.