Yes I take the big three every day. Clarithromycin 500mg every 12 hours. Rifampin 3 capsules (450mg) and Ethambutol 2 tablets (800mg) take together at morning empty stomach with a big glass of water. Waiting for 1 hour I take clarithromycin. I have my nebulizer (levalbuterol,7%salin,2 times a day. I have my Arikayce inhaler once a day around same time.
I didn’t have any side effects from big threes. But Arikayce said effects happened in 4weeks after it was started. I felt very sick. I didn’t stop Arikayce treatment and the side effects gradually stopped. I regained my appetite,energy, and coughing much less. I received culture negative report 2 times (July,August) . Hope it continues to be negative in the future.God help us.