Evenity injection site pain

Posted by neesie0159 @neesie0159, Oct 8, 2023

Last week I had my 3rd Evenity injections. The MA told me with the first ones that they don’t cause sore arms because they’re given subcutaneous instead of IM. I had them in the morning, by evening my arms were very painful and that lasted into the next day. When I called the rheumatology office for advice I was told this never happens. Right. Same experience the second shots, though slightly less pain. Last week I had a different MA give the injections and mentioned the arm pain, she said that shouldn’t happen. Very minimal pain that time until late afternoon, then I was strapping ice packs to my arms.
Has anyone else had injection site pain?

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I have some pain every time I have shots. Not too much. Thats not my problem.
My complaint is that the medical staff - all of them - never acknowledge that we are having side effects.
This is medical gaslighting.

REPLY

I posted this on Sept. 21 in the Anyone taken Evenity (romosozumab) for Osteoporosis? thread:
I've had 2 sets of Evenity injections so far. The 1st time, they gave them in the flabby part of both arms that hangs down : ) She injected slowly, but it wasn't too bad. BUT, by mid afternoon later both began to feel sore; by dinner both were very sore; and by bedtime, they were both extremely sore. I couldn't even bear them touching the sheets. I ended up sleeping in a recliner with my arms across my chest, so the backs of my arms weren't touching anything. And I have a high pain tolerance (3 babies delivered naturally, no meds). My arms were sore with tender (almost painful) lumps were injected for a week with pain radiating almost to my elbow, esp. on the left. The good news is I felt better each day and I carried out my normal active routine, being careful not to bump my arms the first few days and had no other issues.
I decided to have the 2nd set of Evenity injections in my abdomen. MUCH BETTER!!! Just tender to touch for a couple days, with a bit of a lump under the skin where injected. I was able to sleep as usual in bed.
I definitely plan on having the injections in my abdomen, if they'll give them there from now on.
Update: I had my 3rd set of injections on Sept. 26 in my abdomen, also, and had very minimal discomfort : )!!!

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what will they do for you for the pain and if that is not supposed to happen why is it happening. i did hear you mention anyone address the real problem

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@proliamistake

what will they do for you for the pain and if that is not supposed to happen why is it happening. i did hear you mention anyone address the real problem

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I was advised to take ibuprofen and use ice packs. My next door neighbor is a retired nurse, she said any injection can cause pain and they shouldn’t have led me to believe otherwise.

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@vrgarden

I posted this on Sept. 21 in the Anyone taken Evenity (romosozumab) for Osteoporosis? thread:
I've had 2 sets of Evenity injections so far. The 1st time, they gave them in the flabby part of both arms that hangs down : ) She injected slowly, but it wasn't too bad. BUT, by mid afternoon later both began to feel sore; by dinner both were very sore; and by bedtime, they were both extremely sore. I couldn't even bear them touching the sheets. I ended up sleeping in a recliner with my arms across my chest, so the backs of my arms weren't touching anything. And I have a high pain tolerance (3 babies delivered naturally, no meds). My arms were sore with tender (almost painful) lumps were injected for a week with pain radiating almost to my elbow, esp. on the left. The good news is I felt better each day and I carried out my normal active routine, being careful not to bump my arms the first few days and had no other issues.
I decided to have the 2nd set of Evenity injections in my abdomen. MUCH BETTER!!! Just tender to touch for a couple days, with a bit of a lump under the skin where injected. I was able to sleep as usual in bed.
I definitely plan on having the injections in my abdomen, if they'll give them there from now on.
Update: I had my 3rd set of injections on Sept. 26 in my abdomen, also, and had very minimal discomfort : )!!!

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I wasn’t asked where I wanted the injections given, maybe I’ll see next month if they can do my abdomen.

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@neesie0159

I wasn’t asked where I wanted the injections given, maybe I’ll see next month if they can do my abdomen.

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@neesie0159
This is from the Evenity website:
"---------------------------DOSAGE AND ADMINISTRATION-------------------
• Two separate subcutaneous injections are needed to administer the total dose of 210 mg. Inject two syringes, one after the other. (2.1)
• Should be administered by a healthcare provider. (2.1)
• Administer 210 mg subcutaneously once every month for 12 doses in the
abdomen, thigh, or upper arm. (2.2)
• Adequately supplement calcium and vitamin D during treatment. (2.2)

and this is from the package Insert from Drugs.com:Prepare and clean two injection sites, one for each of the two injections. See Figure B.

Figure B
The recommended subcutaneous injection sites include:
● The thigh
● Abdomen, except for a two-inch area right around the navel
● Outer area of upper arm
Prepare and clean two injection sites, one for each of the two injections. See Figure B.

Figure B
The recommended subcutaneous injection sites include:
● The thigh
● Abdomen, except for a two-inch area right around the navel
● Outer area of upper arm

I tried to include a diagram from the Package Insert. But if you put Evenity in your search bar and scroll down to Drugs.com Evenity Injection: Package Insert-Drugs.com, then click on Dosage and Administration, scroll down to 2.3 Preparation and Administration Instructions and read and scroll you'll see the diagram.

I hope that helps.

REPLY
@vrgarden

I posted this on Sept. 21 in the Anyone taken Evenity (romosozumab) for Osteoporosis? thread:
I've had 2 sets of Evenity injections so far. The 1st time, they gave them in the flabby part of both arms that hangs down : ) She injected slowly, but it wasn't too bad. BUT, by mid afternoon later both began to feel sore; by dinner both were very sore; and by bedtime, they were both extremely sore. I couldn't even bear them touching the sheets. I ended up sleeping in a recliner with my arms across my chest, so the backs of my arms weren't touching anything. And I have a high pain tolerance (3 babies delivered naturally, no meds). My arms were sore with tender (almost painful) lumps were injected for a week with pain radiating almost to my elbow, esp. on the left. The good news is I felt better each day and I carried out my normal active routine, being careful not to bump my arms the first few days and had no other issues.
I decided to have the 2nd set of Evenity injections in my abdomen. MUCH BETTER!!! Just tender to touch for a couple days, with a bit of a lump under the skin where injected. I was able to sleep as usual in bed.
I definitely plan on having the injections in my abdomen, if they'll give them there from now on.
Update: I had my 3rd set of injections on Sept. 26 in my abdomen, also, and had very minimal discomfort : )!!!

Jump to this post

I would make sure that the injections are being given at room temperature. I self inject and leave out for at least 1 hour.
So far I haven’t had any pain from the injections.

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I am a retired RN and all injections no matter if the are muscular or subcutaneous can cause some discomfort.

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@kristie2

I am a retired RN and all injections no matter if the are muscular or subcutaneous can cause some discomfort.

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I agree all injections cause some degree of discomfort. I'm a retired RN, too.

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I think most of us know the difference between discomfort and PAIN.

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