What astonishes me is the failure of most physicians to understand and then communicate to their patients the rigorously researched effects of diet modifications around glucose, fructose, ketosis, and intermittent and 7-day fasting on improving standard of care and even acting outside standard of care.

Dr. Thomas Seyfriend, a highly respected scientist and clinician of Yale and now Boston College and many international researchers have been working on metabolic therapy for cancer. This isn't some wacky theory. It fits with Warburg's fundamental theory of how cancer cells survive as well as the emerging evolutionary paradigm of cancer itself. But all the money is in genetics and in these horrid AI drugs.

One study I haven't seen yet--and wouldn't encourage because the mouse torture makes me sick--is comparing the er positive, her 2 negative mice w/ tumors after on AI/Tamoxifen vs a ketogenic diet to then measure tumor shrinkage.

On DIET ALONE (and fasting), Seyfriend and those in his research cohort have shrunk glioblastomas to near nothing. They'll never say they "cure" cancer, but they do say they can help you "manage' cancer. And they're very careful never to challenge standard of care (very openly), though they do , .

I'm about to get prescribed HT therapy and will take the script and not take the pill or else explain outright that I have several comorbidities and the side effects of these drugs would make my life not worth living--and would make my functioning impossible.

Those oncologists who minimize the side effects--are they going to pay our bills when we can't work? Pay for 24/7 nursing care? Help with the ocular side effects, liver? The musculoskeletal pain well documented in over 600 publications as of 2023 that doctors STILL minimize, because it's mostly in women?

I'm sick of it. Once again, women can just go off and suffer. We just need "mindfulness." At least the researchers on AIIMS (aromatase inhibitor induced musculoskeletal syndrome) went to the trouble of identifying through the various physical, scanning, and even genetic tests that the pain wasn't in those silly women's heads. Estrogen plays a major role in mediating pain itself, as well as in healthy tissues everywhere. Why is potentially preventing mets more important than all of the other issues I'm facing?

I'm astonished at the ongoing minimization of the side effects of this therapy (including by plenty of female doctors) and how fundamentally sexist this is. Granted, I haven't gone to prostate therapy boards to see how men are handling it, but I'd bet $100 that if they're in pain or severe anxiety that they'll get the meds they need to function ASAP whereas we'll be treated as lying hypochondriacs.

I'm early low risk too but will decline radiation for my one positive node. I have to be functional--if not, what's the point? My kids are grown. My comorbidities have already stripped so much from me and as a woman my symptoms are still disbelieved despite many stemming from a genetic condition. I need the last years of my life to be as functional as possible. But each to her own way, of course. God bless. Rant /off/ 🙂