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@ken240

I am on Gem/Abrax currently, 3 weeks on, 1 off. I, too, receive Decadron as a pre-med with Aloxi or Zofran. I was thinking about asking my oncologist to reduce the Decadron dose because I think it causes insomnia. May I ask why your dose was reduced?

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Replies to "I am on Gem/Abrax currently, 3 weeks on, 1 off. I, too, receive Decadron as a..."

I'm not the poster you're querying, but yes, I agree that dexamethasone causes insomnia, at least for the first night or two. I always feel pumped up on the steroid for 24-48 hours, and then it begins to wane. I also think it causes hiccups, as least for me.

The Decadron dose was reduced due to the thinking that the swelling in my feet & ankles & whole body might be related to it as it is a steroid. Not sure if that changed much for the swelling. I too have insomnia the first and sometimes second nights of getting the Decadron. That did not change when I got the lower dose. I was still "wired" the night of chemo and the next. Lack of sleep & steroid equals one cranky person 🙂 Try to stay away from people who do not get it & that ends up being most people 🙂