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Anyone have experience with anal intraepithelial neoplasia (AIN)?

Colorectal Cancer | Last Active: Jun 16, 2024 | Replies (28)
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@nc64

Hello,
I have been recently diagnosed with AMI3. This was found during a routine gyn exam. I had a punch biopsy first with a result of HPV 16. I had further exam under anesthesia with biopsy which showed AMI3.
My surgeon recommend exam every 3 months, and Aldara cream. The margins were not clear with the biopsy. I am 64 female, with one partner for 30 years. No anal sex, just trying to figure this out. Is there any other treatment options??
I am scheduled for another exam in November to see if he can get the margins clear, although the surgeon says it is doubtful.

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Replies to "Hello, I have been recently diagnosed with AMI3. This was found during a routine gyn exam...."
Colleen Young, Connect Director | @colleenyoung | Oct 12, 2023

Hi @nc64, fellow members like @shaerical @wastars1 @amyb5 @ouchy @rioa21 @dilemma6 will join me in welcoming you.

There may be other treatment options available to you. If I were in your situation, I would want to better understand why the margins are not clear and what can be done. How long ago was the biopsy? Why the wait? Have you considered getting a second opinion?

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rioa21 | @rioa21 | Oct 12, 2023

I’m sorry to hear that you’re going though this. I’ve just come out the other side of a battle with anal cancer. Mine was squamous cell caused by HPV. You can have the virus for years and not know it. It sounds like you owe it to yourself to get another opinion. I’m not a doctor, but not getting clear margins on a biopsy sounds odd. Do some research on your own and find a doctor with lots of experience in dealing with this.

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