Hi @rtresher1
First of all, kudos to you for being in such good health generally. I don't read a lot of that on these message boards.

This message is not medical advice, just reason to have hope. Just reading your story, my gut reaction is that going off Crestor is related. Like many meds, I read that statins are a med you need to go off of slowly to avoid withdrawal symptoms. I've had withdrawal issues from going off different meds and they can be crazy and last for weeks or months. I also read that one of the issues going off statins can cause is peripheral neuropathy and symptoms of that include twitching and muscle cramps among others. You know the statins caused muscle cramps for you so it makes sense going off of it could impact muscles as well. Since withdrawal is a possibility, it seems there is hope that the fasciculations will resolve on their own. They are very annoying and only noticeable at rest as you have discovered. Good that you sought advice from a neurologist who believes it's BFS and harmless all except for driving you nuts.

I had fasciculations for years starting in my 20s due to my neuropathy then suddenly they stopped from about 40-55 years old. It was a mystery why until I went off atenolol, a beta-blocker for blood pressure. Within days, the fasciculations were back with a vengeance and turned into violent muscle jerks and cramps in my feet and calves within 5 minutes of resting. I was jumping out of my chair and bed all night. I had been on atenolol for 15 years. Aha! I started taking the atenolol again, the cramps stopped and facsiculations improved about 80% over time, but never completely went away again. Darn. Now one of my cancer meds has caused my blood pressure and heart rate to be dangerously low so I really need to be off atenolol as its piling on. I'm trying to wean off slowly this time. I cut my dose in half a week ago and already the fasciculations have really increased in my legs and now in both eyelids which really drives me nuts. No muscle jerks or cramps yet though. I'll do this dose for a month, then if still tolerable, I'll try cutting it in half again and then zero. Not sure I can completely go off, but both my heart rate and blood pressure have already gone up and are closer to low normal now so I'm hopeful I can at least stay on this lower dose for improved health. I really don't like meds. They are a bartering system of trading one issue for another. Sometimes it's a good trade, sometimes not.

Praying that your BFS issues are only temporary. 🙂 Oh caffeine and chocolate (which has some caffeine) will make all my neuro issues worse so maybe test cutting back on any caffeine just to see. Best of luck to you! Zebra