My HES affected my heart. Nucala has been approved by the FDA to treat HES and I take 300 ml a month. (three 100 ml shots). First time February and it has ben terrific. My eosinophils have been normal this whole time. I also have eosinophilic myocarditis. Up until now I have had zero side effects. Just wondering if anyone else has had an itching problem. Working on process of elimination to get it to stop.