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PSA after 20 Proton treatments

Prostate Cancer | Last Active: 14 hours ago | Replies (43)

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@jc76

Wow the feedback on PSA after treatments is very wide. Seems the high dose lower amount of treatments comes back with lower PSA after last treatment.

I went from 3.75 to 1.2 three months after last treatment. I am told the prostrate is still very irritated and will take some time to get a base PSA to use for diagnosis graphing. My oncologist team said if you have drop of half of your PSA after 3 months is considered good. I guess my next one will be more informational as my side affects continue to improve.

But sure wish mine had came back like some posting undetectable. But 20 years ago my PSA was always .75 year after year so maybe should be more happier with a 1.2.

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Replies to "Wow the feedback on PSA after treatments is very wide. Seems the high dose lower amount..."

My doc said a nadir of between 1 and 2 is considered a success. However, this is from Google AI Bard. Keep in mind that the answers given are not always correct. Given the numbers people here at 12 months post radiation are quoting, between 1.0 and 2.0 seems a common nadir.

“There is no single "normal" PSA level after proton beam therapy (PBRT) for prostate cancer. PSA levels can vary widely from person to person, and even from day to day. However, most men who achieve a PSA nadir (lowest level) of 0.2 ng/mL or less after PBRT can expect to remain disease-free.

A PSA nadir of 0.2 ng/mL or less is considered a good PSA level after PBRT. However, some men may have PSA levels that are slightly higher than this and still remain disease-free. Conversely, some men may have PSA levels that are lower than 0.2 ng/mL and still experience a recurrence of prostate cancer.

Other factors that can affect PSA levels after PBRT include:

The stage and grade of the prostate cancer before treatment
The total dose of radiation delivered
The type of radiation therapy used (PBRT or external beam radiation therapy)
The presence of other medical conditions
It is important to discuss your PSA levels with your doctor after PBRT to determine what is considered a good PSA level for you. Your doctor will also monitor your PSA levels over time to look for any signs of recurrence.

If your PSA level rises above 1 ng/mL or 2 ng/mL above your nadir, your doctor may recommend further testing, such as a prostate biopsy, to determine if the cancer has returned.

Here are some general guidelines for PSA levels after PBRT:

PSA nadir of 0.2 ng/mL or less: Good PSA level, most men with this level will remain disease-free.
PSA nadir of 0.2-1 ng/mL: Acceptable PSA level, some men with this level may remain disease-free, but others may experience a recurrence of prostate cancer.
PSA nadir above 1 ng/mL: PSA level that may warrant further testing and monitoring.
It is important to note that these are just general guidelines. Your doctor will discuss your PSA levels with you individually to determine what is considered a good PSA level for you.”