I can relate to many things on this thread. I have side effects to many drugs. I had sciatica off and on in my 50’s and 60’s. Now at 73? Seems like everything hit at once. I believe Covid brought everything out that was in my body: hereditary diabetes, hereditary Glaucoma, Hashimodo’s Disease and fibromyalgia along with the neuropathy and Long Covid. Many of these problems have similar issues so they overlap. Beta blockers in my eye drops were particularly bad for side effects. I had such a hard time with neurology and fibromyalgia pain at night I would cry and walk the floors. Gabapetin didn’t work. I started seeing an Osteopath who really helped me. He understands that my body is very sensitive to medication and supplements. I was prescribed methadone in very low dose which let me sleep at night. Then I was taken off that and prescribed Baclofen (muscle/nerve relaxer without side effects for me) in low dose which really helps me. Using stretch bands and 2 lb dumbbells for my shoulders and arms (fibromyalgia) and treadmill for my legs and feet and knees (both fibro and neuropathy) and stretching. It’s a slow process and I have my up and down days but I’m better. Hope you find a doctor who listens to you and works on a plan for your entire body like my Osteopath. Hang in there you will find what helps you!!