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DiscussionAnyone taken Evenity (romosozumab) for Osteoporosis?
Osteoporosis & Bone Health | Last Active: 5 days ago | Replies (1363)Comment receiving replies
Replies to "I will post about Actonel when it's been a bit. I haven't taken it yet as..."
Unfortunately you and I seem to be among the very, very few people who seem to have more of a reaction to the drug. I noticed while being on Evenity, though the pain in my hands increased with each dose after month 5, the pain did decrease until the next dose. The half-life of Evenity is 12 days so each 12 days the amount of Evenity in your system should decrease by half; 50%, 25%, 12.5% etc. So I would say that after discontinuing Evenity the pain was getting better but I took Reclast 6 weeks after dose 9 so it's hard to say if I had waited longer the pain would have gotten even better. I seem to recall that some people on this forum said that any pain they were having decreased or went away with time. The bottom line is everyone has different reactions and the vast majority have no problems at all.
From what I've read I got the impression that when you stop the drugs joint pain or any adverse reactions decrease/go away but will return when you take the medication again. Of course, I haven't been able to find or figure out when the adverse reactions actually go away.