@neri47 yet your doctor still refills your prescription? The long term negative effects of prednisone are well known. From blood vessel breakdown, kidney damage, weight gain just to name a few. Your doc is correct and there are other less harmful meds for inflammation you can take. Although, you don’t say why you’re taking it? Then again at 76 you are making your own life choices and me at 71 cannot knock you for your choice but, I just want to make you aware of the dangers. Living your last years suffering from one of the nasty adverse effects of long term prednisone use will be no pick nick for you and I wish you well.