@artisan3 you can do Reclast or another bisphosphonate after Evenity to "lock in gains." I have been told that I might be able to take a medication break after one or two infusions of Reclast following Tymlos, with adequate monitoring. Prolia is difficult to get off and according to my docs and McCormick's new book "Great Bones," the process of getting off requires careful timing of transition to Reclast to avoid sudden bone loss.