We are all different. I am 76, gleason 9 CR aggressive, advanced PC. I was in lupron and Erleada 6 months before RP and then 6 months after. None of that was terrible but I felt a bit worse than normal. My T dropped to 9, after the first 13 months then 24, then and now T 93. I have been off of all meds for 9 months got low T , PSA .01 and feeling generally great and sincerely thankful for the excellent care at UCLA. I am now on a veggie only diet per doctors instructions I have not had the terrible side effects from meds and I am hopeful. My doctor has advised that PC will not kill me and I suspect that he said that as he knows about my traffic and freeways in LA!