Hi @kaprizzz, I also have an extremely high ANA with some type of titer. I really don't remember the Titer part. Anyhow, I was also negative on everything else. No RA, lupus, MS, etc. I do; however, have more than one autoimmune disease. Hashimotos thyroiditis, Sjogrens, and Raynaud's syndrome. I also have bladder cancer. Doctors told me high ANA can be from the autoimmune diseases. I also found out there is something called sero negative lupus, RA, etc. If a person has all of the signs and symptoms of RA, for example, but all of the blood work is negative for RA they could be diagnosed as having sero negative Rheumatoid Arthritis.
Good luck on finding out what is causing your pain. May God Bless you with peace and comfort from your pain, and give the doctors the guidance they need to find out what is causing your ANA to be high 🙏😄🌞