I have only been on Fosimax for 2 months. I started taking it just after I stopped Evenity which I was on for 5 months. I had to stop due to side effects. I have no side effects from the Fosimax. I would caution you on taking Prolia and encourage you to read " Great Bones" by R Keith McCormick which several people on this site also recommend. He discusses each medication for Osteoporosis and lab tests, supplements needed when having Osteoporosis.