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Concerned about the side effects of anastrozole

Breast Cancer | Last Active: 6 days ago | Replies (1931)

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@tamtam24

Has anyone found any significant difference in hair thinning between the various inhibitors? I've been on Anastrozole for about a year and a half. I have knee pain/stiffness when I get up from a chair or walk up and down stairs, but once I get going on a flat surface, no pain. I also have chronic tiredness and terrible insomnia. However, I can live with all those. The hair thinning is particularly tough for me because I already struggled for years with androgenic alopecia. Fortunately, it was mostly around the hairline and on top and I have naturally wavy/curly hair, so even the dermatologist I saw a few years ago had to get right on top of me to notice. I then started taking Rogaine, which seemed to stabilize my hair. However, since being on the Anastrozole, the thinning seems much worse. I don't lose hair, just each hair is so thin. I've had two really humiliating experiences recently where I was in a picture and shocked at how noticeable my thinning has become. I know that the hormone therapy is key, but, boy, I already felt so bad about myself and how I looked, and now I feel so defeated and depressed. Any insights? Experiences? Advice? Thanks for listening!

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Replies to "Has anyone found any significant difference in hair thinning between the various inhibitors? I've been on..."

I am also on Anastrozole and hair thinning with insomnia are my biggest issues. The drastically thinning hair is the hardest for me as well. Looking in the mirror is that constant reminder that I am not the same person I was before diagnosis in July 2022. I also have androgenic alopecia & frontal fibrosing Alopecia. This hair loss is all over my head. I do see my oncologist tomorrow and plan to ask if I can try another AI. Really discouraging, but then is this hair loss worth not being on an AI. For now my answer is no, but that could change if this hair loss doesn’t slow down.