I had a biopsy to see if I had endometrial cancer so I think it is the same type of biopsy you are referring to, but I’m not sure. The nurse suggested I take 3 Advils 1 hour before my appointment. It helped and I got through it. I see you have had 3 c-sections. I have never been pregnant so I don’t know much about pain and I have to say the biopsy procedure went quickly. A nurse was there as the Gyn performed the procedure and helped me with breathing to help keep me relaxed and focus.